Glucosamine sulfate occurs naturally in human cartilage and is also synthesized from chitin, a polysaccharide and amide derivative of glucosamine obtained from the shells of lobsters, crabs and other shellfish. Because chitin is also a component of cellular walls in yeast and fungi, glucosamine sulfate powder is also produced from fermented grains.
Glucosamine sulfate powder is typically encapsulated as a dietary supplement. However, it is also used in skin care products.