Cascara sagrada, which means “sacred bark,” refers to the bark of a
shrubby tree that is native to the American Pacific Northwest. The bark
must be aged for at least a year before use to give enough time for the
anthrone glycosides in the bark to degrade. Otherwise, these compounds
would produce strong purgative effects, including intestinal cramping
and vomiting.
Today, cascara sagrada is primarily valued for its role in traditional herbal systems and for its significance as a classic botanical ingredient. As with many traditional herbs, it is best approached with care and used in accordance with applicable guidelines and professional advice. Cascara sagrada is
permitted as a dietary supplement, but this herb should not be used for
more than a week and must be taken with sufficient fluids.